Clinical trial of a post-coital contraceptive pill.

The study of a post-coital contraceptive pill containing 0.75 mg levonorgestrel was undertaken at National Research Institute of Fertility Control (NRIFC) to assess its efficacy, side effects and acceptability. Ninety five women were studied for 340 months of use. Average age and parity of acceptors was 29.4 and 3.8 respectively. Menstrual cycle irregularity was the most prominent sideeffect responsible for 42.1% of discontinuations. No serious medical complications were noted. Contraceptive failure (pregnancy) rate calculated according to modified Pearls formula was 2.5 per 100 women years. The post-coital pill found acceptance in a group of women who needed contraception infrequently. Results are discussed comparing the experience with other contraceptives (JPMA 38:105, 1988).